Insulin yamunthu… yochokera kwa msilikali wakuda akuwuluka? FlyBlast anafunsa funso

Khalani pamwamba pazomwe zikuchitika padziko lonse lapansi pazakudya, ulimi, ukadaulo wanyengo komanso ndalama zokhala ndi nkhani zamakampani komanso kusanthula.
Pakadali pano, mapuloteni ophatikizananso amapangidwa ndi tizilombo tating'onoting'ono tating'onoting'ono tachitsulo. Koma tizilombo ting'onoting'ono titha kukhala anzeru, makamu azachuma kwambiri, akuti FlyBlast yochokera ku Antwerp, yomwe imasintha ntchentche zankhondo zakuda kuti zipange insulin ndi mapuloteni ena ofunikira.
Koma kodi pali zowopsa ku njira yoyambilira ya kampani yolunjika kumakampani omwe angoyamba kumene komanso opanda ndalama?
AgFunderNews (AFN) adakumana ndi woyambitsa komanso CEO Johan Jacobs (JJ) ku Future Food Tech Summit ku London kuti aphunzire zambiri…
DD: Ku FlyBlast, tasintha chibadwa cha ntchentche ya msilikali wakuda kuti ipange insulini yaumunthu ndi mapuloteni ena ophatikizana, komanso zinthu zomwe zimakula zomwe zimapangidwira kukulitsa nyama (pogwiritsa ntchito mapuloteni okwera mtengowa muzofalitsa zama cell).
Mamolekyu monga insulini, transferrin, IGF1, FGF2 ndi EGF amawerengera 85% ya mtengo wa chikhalidwe cha chikhalidwe. Popanga ma biomolecule awa m'malo osinthira tizilombo, titha kuchepetsa mtengo wawo ndi 95% ndikugonjetsa vutoli.
Ubwino waukulu wa ntchentche za msilikali wakuda [pa tizilombo tating'onoting'ono tomwe timapanga ma genetic ngati njira yopangira mapuloteni oterowo] ndikuti mutha kukulitsa ntchentche zankhondo zakuda pamlingo wochepera komanso pamtengo wotsika chifukwa bizinesi yonse yakulitsa kusinthika kwazinthu zopangidwa mwachilengedwe kukhala mapuloteni a tizilombo. ndi lipids. Tikungokweza mulingo waukadaulo ndi phindu chifukwa mtengo wa mamolekyuwa ndiwokwera kwambiri.
Mtengo waukulu [wosonyeza insulini mu ntchentche zankhondo zakuda] ndi wosiyana kwambiri ndi [mtengo wowotchera mwatsatanetsatane pogwiritsa ntchito tizilombo toyambitsa matenda], ndipo mtengo wake umalipiridwa ndi mankhwala opangidwa ndi tizilombo. Ndi njira ina yopezera ndalama pamwamba pa zonsezo. Koma muyeneranso kuganizira kuti mamolekyu omwe tikuyang'ana ndi mapuloteni enieni a nyama. Ndikosavuta kupanga mamolekyu anyama mu nyama kuposa yisiti kapena mabakiteriya.
Mwachitsanzo, mu kafukufuku wotheka tidawona kaye ngati tizilombo tili ndi njira ngati insulin. Yankho ndi lakuti inde. Tizilombo tating'onoting'ono timafanana kwambiri ndi insulin yamunthu kapena ya nkhuku, chifukwa chake kufunsa tizilombo kuti tipange insulin yamunthu ndikosavuta kuposa kufunsa mabakiteriya kapena zomera zomwe zilibe njira iyi.
JJ: Timayang'ana kwambiri nyama yolimidwa, yomwe ndi msika womwe ukufunikabe kutukuka, kotero pali zoopsa. Koma popeza awiri mwa omwe adayambitsa nawo amachokera ku msika umenewo (mamembala angapo a gulu la FlyBlast adagwira ntchito ku Antwerp-based artificial fat startup Peace of Meat, yomwe inathetsedwa ndi mwiniwake wa Steakholder Foods chaka chatha), timakhulupirira kuti tili ndi luso. kuti izi zichitike. Amenewo ndi amodzi mwa makiyi.
Pamapeto pake, nyama yodulidwa idzapezeka. Zidzachitikadi. Funso ndi liti, ndipo ili ndi funso lofunika kwambiri kwa osunga ndalama athu, chifukwa amafunikira phindu mu nthawi yoyenera. Ndiye tikuyang'ana misika ina. Tidasankha insulin kukhala chinthu chathu choyamba chifukwa msika wolowa m'malo unali wodziwikiratu. Ndi insulin yaumunthu, ndiyotsika mtengo, ndiyotheka, kotero pali msika wonse wa shuga.
Koma kwenikweni, nsanja yathu yaukadaulo ndi nsanja yabwino kwambiri… Pa nsanja yathu yaukadaulo, titha kupanga mamolekyu ambiri a nyama, mapuloteni, ngakhalenso michere.
Timapereka mitundu iwiri ya chithandizo chowonjezera ma genetic: timalowetsa majini atsopano mu DNA ya ntchentche yakuda, ndikupangitsa kuti iwonetse mamolekyu omwe sapezeka mwachilengedwe mumtundu uwu, monga insulin yamunthu. Koma tithanso kufotokoza mochulukira kapena kupondereza majini omwe alipo mumtundu wa DNA kuti tisinthe zinthu monga mapuloteni, amino acid mbiri, kapena mafuta a asidi (kudzera m'mapangano a chilolezo ndi alimi / okonza tizilombo).
DD: Limenelo ndi funso labwino kwambiri, koma awiri mwa omwe adandiyambitsa nawo ali m'makampani olima nyama, ndipo amakhulupirira kuti [kupeza zopangira zotsika mtengo zama cell monga insulini] ndiye vuto lalikulu kwambiri pamsika, komanso kuti makampaniwa alinso ndi kukhudza kwambiri nyengo.
Zachidziwikire, tikuyang'ananso msika wamankhwala wa anthu komanso msika wa shuga, koma tikufunika sitima yayikulu kuti izi zitheke chifukwa pongofuna kuvomerezedwa, muyenera $ 10 miliyoni kuti mupange zolemba, kenako muyenera kupanga. otsimikiza kuti muli ndi molekyulu yoyenera pa chiyero choyenera, ndi zina zotero. Titengapo masitepe angapo, ndipo tikafika pa malo otsimikizira, tikhoza kupeza ndalama zogulitsira msika wa biopharma.
J: Zonse ndi za makulitsidwe. Ndinayendetsa kampani yaulimi wa tizilombo [Millibeter, yogulidwa ndi [yomwe tsopano yatha] AgriProtein mu 2019] kwa zaka 10. Chifukwa chake tidayang'ana tizilombo tosiyanasiyana, ndipo chinsinsi chinali momwe tingakulitsire kupanga modalirika komanso motsika mtengo, ndipo makampani ambiri adamaliza kupita ndi ntchentche zankhondo zakuda kapena nyongolotsi. Eya, zedi, mutha kulima ntchentche za zipatso, koma ndizovuta kuzikulitsa mochulukirapo m'njira yotsika mtengo komanso yodalirika, ndipo mbewu zina zimatha kupanga matani 10 a biomass tsiku lililonse.
JJ: Choncho mankhwala ena a tizilombo, mapuloteni a tizilombo, lipids tizilombo, ndi zina zotero, zikhoza kugwiritsidwa ntchito mu ndondomeko yamtengo wapatali ya tizilombo, koma m'madera ena, chifukwa ndi mankhwala osinthidwa, sangavomerezedwe ngati chakudya cha ziweto.
Komabe, pali ntchito zambiri zaukadaulo kunja kwa mayendedwe azakudya zomwe zimatha kugwiritsa ntchito mapuloteni ndi lipids. Mwachitsanzo, ngati mukupanga mafuta am'mafakitale pamafakitale, zilibe kanthu kuti lipidyi imachokera ku gwero losinthidwa ma genetic.
Ponena za manyowa [chimbudzi cha tizilombo], tiyenera kusamala powatengera kuminda chifukwa ali ndi ma GMO, motero timawapaka kukhala biochar.
DD: Pasanathe chaka chimodzi… tinali ndi mzere wokhazikika woswana wosonyeza insulini yamunthu mochuluka kwambiri. Tsopano tikufunika kuchotsa mamolekyu ndikupereka zitsanzo kwa makasitomala athu, kenako timagwira ntchito ndi makasitomala pa mamolekyu omwe amafunikira pambuyo pake.
       


Nthawi yotumiza: Dec-25-2024