Hlala uphezulu kokuthrendayo emhlabeni jikelele kokudla, ezolimo, ubuchwepheshe besimo sezulu kanye nokutshalwa kwezimali ngezindaba ezihamba phambili zemboni nokuhlaziya.
Njengamanje, amaprotheni ahlanganisiwe ngokuvamile akhiqizwa ama-microorganisms kuma-bioreactors ensimbi amakhulu. Kepha izinambuzane zingaba ngobuhlakani, abasingathi abangonga kakhulu, kusho i-FlyBlast esekwe e-Antwerp, eguqula ngokofuzo izimpukane zamasosha amnyama ukuze zikhiqize i-insulin namanye amaprotheni abalulekile.
Kodwa ingabe zikhona izingozi zesu lokuqala lenkampani lokukhomba imboni yenyama esafufusa kanye neboshiwe ngemali?
I-AgFunderNews (AFN) ihlangane nomsunguli kanye ne-CEO uJohan Jacobs (JJ) engqungqutheleni ye-Future Food Tech eLondon ukuze ufunde kabanzi…
DD: Kwa-FlyBlast, siguqule ufuzo impukane yesosha elimnyama ukuze ikhiqize i-insulin yomuntu kanye namanye amaprotheni ayinhlanganisela, kanye nezici zokukhula eziklanyelwe ngokukhethekile ukutshala inyama (sisebenzisa lawa maphrotheni abizayo emithonjeni yemidiya yamaseli).
Amangqamuzana anjenge-insulin, i-transferrin, i-IGF1, i-FGF2 ne-EGF abiza u-85% wezindleko zesiko lesiko. Ngokukhiqiza ngobuningi lawa ma-biomolecules ezindaweni zezinambuzane ze-bioconversion, singanciphisa izindleko zazo ngo-95% futhi sinqobe le nkinga.
Inzuzo enkulu yezimpukane zamasosha amnyama [ngaphezu kwama-microorganisms aguqulwe ngofuzo njengendlela yokukhiqiza amaprotheni anjalo] ukuthi ungakwazi ukukhulisa izimpukane zamasosha amnyama ngesilinganiso nangezindleko eziphansi ngoba imboni yonke ikhuphule ukuguqulwa kwe-bioconversion yemikhiqizo etholakalayo ibe amaprotheni ezinambuzane. kanye ne-lipids. Sikhuphula izinga lobuchwepheshe kanye nenzuzo ngoba inani lala ma-molecule liphezulu kakhulu.
Izindleko ezinkulu [zokuveza i-insulin ezimpukaneni zamasosha amnyama] zihluke ngokuphelele [ezindlekweni zokuvutshelwa okunembayo kusetshenziswa ama-microorganisms], futhi izindleko ezinkulu zihlanganiswa nemikhiqizo yezinambuzane ezivamile. Kungenye nje indlela yokuthola imali phezu kwakho konke lokho. Kodwa futhi kufanele ucabange ukuthi ama-molecule esiwaqondise angamaprotheni athile ezilwane. Kulula kakhulu ukukhiqiza ama-molecule ezilwane ezilwaneni kunasemvubelo noma amagciwane.
Isibonelo, ocwaningweni olunokwenzeka siqale sabheka ukuthi izinambuzane zinendlela efana ne-insulin yini. Impendulo ithi yebo. I-molecule yezinambuzane ifana kakhulu ne-insulin yomuntu noma yenkukhu, ngakho-ke ukucela izinambuzane ukuthi zikhiqize i-insulin yomuntu kulula kakhulu kunokubuza amagciwane noma izitshalo, ezingenayo le ndlela.
JJ: Sigxile enyameni egayiwe, okuyimakethe okusamele ithuthukiswe, ngakho kunezingozi. Kodwa njengoba ababili engangibambisene nabo bevela kuleyo makethe (amalungu amaningana eqembu le-FlyBlast asebenze ekuqaleni kwamafutha okufakelwa ase-Antwerp i-Peace of Meat, eyaqedwa ngumnikazi wayo i-Steakholder Foods ngonyaka odlule), sikholelwa ukuthi sinamakhono. ukwenza lokhu kwenzeke. Lokho kungenye yezihluthulelo.
Inyama egayiwe izogcina isikhona. Kuzokwenzeka nakanjani. Umbuzo uthi nini, futhi lona umbuzo obaluleke kakhulu kubatshalizimali bethu, ngoba badinga inzuzo ngesikhathi esifanele. Ngakho sibheka ezinye izimakethe. Sakhetha i-insulin njengomkhiqizo wethu wokuqala ngoba imakethe yokushintsha yayisobala. Kuyi-insulin yomuntu, ishibhile, iyahlaziywa, ngakho-ke kukhona imakethe yonke yesifo sikashukela.
Kodwa empeleni, inkundla yethu yobuchwepheshe iyinkundla enhle kakhulu… Kuplathifomu yethu yobuchwepheshe, singakhiqiza ama-molecule ezilwane, amaprotheni, ngisho nama-enzyme.
Sinikeza izinhlobo ezimbili zezinsizakalo zokuthuthukisa izakhi zofuzo: sethula izakhi zofuzo ezintsha ngokuphelele ku-DNA yempukane yamasosha amnyama, siyivumela ukuthi iveze ama-molecule angekho ngokwemvelo kulolu hlobo, njenge-insulin yomuntu. Kodwa futhi singakwazi ukucindezela ngokweqile noma ukucindezela izakhi zofuzo ezikhona ku-DNA yohlobo lwasendle ukuze siguqule izakhiwo ezifana nokuqukethwe kwamaprotheni, iphrofayili ye-amino acid, noma ukwakheka kwe-acid enamafutha (ngezivumelwano zamalayisensi nabalimi/abacubungula izinambuzane).
DD: Umbuzo omuhle ngempela lowo, kodwa ababili engibambisene nabo basembonini yenyama ekhulisiwe, futhi bakholelwa ukuthi [ukuthola izithako ezishibhile zamaseli njenge-insulin] kuyinkinga enkulu embonini, nokuthi imboni nayo ine umthelela omkhulu esimweni sezulu.
Yebo, sibheka imakethe yemithi yabantu kanye nemakethe yesifo sikashukela, kodwa sidinga umkhumbi omkhulu walokho ngoba mayelana nokuthola imvume yokulawula, udinga ama- $ 10 wezigidi ukwenza amaphepha, bese udinga ukwenza uqinisekile ukuthi une-molecule elungile ekuhlanzekeni okufanele, njll. Sizothatha izinyathelo ezimbalwa, futhi uma sifika endaweni ethile yokuqinisekisa, singaqongelela imali yemakethe ye-biopharma.
J: Konke kumayelana nokukala. Nganginenkampani yokulima izinambuzane [i-Millibeter, etholwe yi-AgriProtein [engasasebenzi] ngo-2019] iminyaka eyi-10. Ngakho-ke sibheke izinambuzane eziningi ezihlukene, futhi ukhiye kwakuwukukhuphula umkhiqizo ngendlela ethembekile futhi eshibhile, futhi izinkampani eziningi zagcina zihamba nezimpukane zamasosha amnyama noma izikelemu zokudla. Yebo, impela, ungatshala izimpukane zezithelo, kodwa kunzima ngempela ukuzikhulisa ngobuningi ngendlela eshibhile nethembekile, futhi ezinye izitshalo zingakhiqiza amathani ayi-10 e-biomass yezinambuzane ngosuku.
JJ: Ngakho eminye imikhiqizo yezinambuzane, amaprotheni ezinambuzane, amafutha ezinambuzane, njll., ngokobuchwepheshe ingasetshenziswa ochungechungeni lwenani lezinambuzane ezivamile, kodwa kwezinye izindawo, ngenxa yokuthi iwumkhiqizo oshintshwe izakhi zofuzo, ngeke yamukelwe njengokudla kwemfuyo.
Kodwa-ke, kunezinhlelo eziningi zobuchwepheshe ngaphandle kochungechunge lokudla ezingasebenzisa amaprotheni nama-lipids. Isibonelo, uma ukhiqiza amafutha embonini ngesilinganiso semboni, akunandaba ukuthi i-lipid isuka emthonjeni oshintshwe ufuzo.
Mayelana nomquba [indle yezinambuzane], kufanele siqaphele ngokuwuhambisa emasimini ngoba uqukethe imikhondo yama-GMO, ngakho siyawugaxa ube yi-biochar.
DD: Phakathi nonyaka… saba nomugqa wokuzalanisa ozinzile oveza i-insulin yomuntu ngesivuno esiphezulu kakhulu. Manje sidinga ukukhipha ama-molecule futhi sinikeze amasampula kumakhasimende ethu, bese sisebenzisana namakhasimende ukuthi yimaphi ama-molecule awadingayo ngokulandelayo.
Isikhathi sokuthumela: Dec-25-2024